Cd300a macrophage
WebJun 24, 2014 · These results identify CD300a-mediated inhibitory signaling in macrophages as a critical regulator of intestinal immune homeostasis. Scientific Reports - PPARβ/δ activation of CD300a controls ... Web蛋白酪氨酸磷酸酶C型受體 （英語： Protein tyrosine phosphatase, receptor type, C ， 縮寫 ： PTPRC ）是一個由PTPRC 人類 基因 編碼的 酶 [6] 蛋白酪氨酸磷酸酶C型受體又叫做45號 分化簇 抗原 ，以前曾叫 白細胞常見抗原 （英語： leukocyte common antigen ， 縮寫 …
Cd300a macrophage
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WebJun 2, 2011 · CD300a belongs to the CD300 family of activating/inhibitory receptors whose genes are clustered in human chromosome 17. 12 CD300a is a type I transmembrane receptor with an IgV-like extracellular domain and a cytoplasmic tail that has 3 classic ITIM motifs 12,13 and is expressed on cells of both lymphoid and myeloid lineages. 12 Its … WebJan 6, 2012 · CD300a is expressed on a variety of cell lineages, including mast cells, granulocytes, dendritic cells and macrophages. It is an exclusively important issue to explore the functional role of CD300a as a PS receptor in regulation of immune responses.
WebMar 29, 2024 · CD300a induction by the hypoxic environment represents a mechanism of regulation of monocyte/macrophage pro-inflammatory responses at pathologic sites Title: Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages. WebJun 24, 2014 · Peritoneal macrophages from Cd300a-/- mice on HFD are classically M1 activated. Activation of toll-like receptor 4 (TLR4)/MyD88 signaling by lipopolysaccharide (LPS) results in prolonged IL-6 ...
WebMar 22, 2012 · Abstract. CD300a is an immunoreceptor tyrosine-based inhibitory motif (ITIM) containing molecule that belongs to the CD300 family of paired …
WebOct 15, 2024 · To examine the role of CD300a in ischemia-induced pathology, we injected Cd300a fl/fl and Cd300a fl/fl Lyz2-Cre mice with …
WebJan 1, 2014 · In mice, disruption of the Cd300a gene resulted in pro-inflammatory activation of peritoneal macrophages, identifying CD300a-mediated inhibitory signaling in macrophages as a critical regulator of ... my wallpapersWebMay 12, 2024 · LPC is released from apoptotic cells and binds to the G-protein-coupled receptor G2A on macrophages, ... Choi SC, Coligan JE, Borrego F . Human CD300a binds to phosphatidylethanolamine and ... the simpsons neighbor flandersWebMar 14, 2013 · The CD300 family of molecules modulates a broad and diverse array of immune cell processes via their paired activating and inhibitory receptor functions. … my wallpaper todayWebApr 8, 2024 · CD8 + T cells, M0 macrophages, and M2 macrophages were significantly different in the high- and low-risk subgroups (Fig. 10C). As expected, the 8 hub genes were closely related to immune cell ... the simpsons nelson hahaWebJun 24, 2014 · Based on these finding we propose that CD300a, a novel PPARβ/δ target gene in macrophages, maintains intestinal immune response. In wild type mice, HFD-derived fatty acids can activate the … the simpsons netflix\u0027te var mıWebMar 26, 2024 · CD300a is expressed by myeloid cells , lymphoid cells, monocytes, macrophages, mast cells, granulocytes, DCs, NK cells and subsets of B and T cells . … my wallpapers folderWebJun 2, 2011 · CD300a down-regulates BCR-mediated activation signals. (A) Purified human B cells (upper panel) or DT40 cells expressing CD300a (lower panel) were loaded with Fluo-4 and Fura-Red. ... In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of … the simpsons nes game