Drp1 phospho s637

Author: zgpy

August undefined, 2024

Web动力相关蛋白1(Drp1)是调节线粒体分裂的关键蛋白。缺血再灌注可引起Drp1 Ser637位点去磷酸化，促进Drp1向线粒体外膜转移，进一步导致线粒体片段化和细胞色素c(Cyt c)过度释放而诱发细胞凋亡 [6,7] 。异丙酚能否通过调控Drp1表达减轻肝脏冷缺血再灌注后肾损伤尚不 ... WebInvitrogen Anti-Phospho-DRP1 (Ser637) Polyclonal, Catalog # PA5-37534. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse, Rat samples. …

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WebIn this study, we address the role of Drp1 phosphorylation at Ser-637 (Drp1 pS637) for subcellular localization and ability to regulate mitochondrial … WebWhen phosphorylated at Ser616, DRP1 stimulates mitochondrial fission during mitosis. Conversely, fission is inhibited when DRP1 is phosphorylated at Ser637 (reviewed in 6). Dephosphorylation at … nightjar close horndean

Phospho-DRP1 (Ser637) (D3A4) Rabbit mAb - Cell …

WebPhospho-DRP1 (S637) Polyclonal Antibody detects endogenous levels of DRP1 protein only when phosphorylated at S637. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. WebJan 4, 2024 · a, b Representative Western blot images of phospho-Drp1 (S637), phospho-Drp1 (S616), and Drp1 in different groups. Then, additional treatment of the OxyHb + APNp group with compound C (Cc, a selective AMPK inhibitor) was used as a negative control. WebDRP1 Antibodies. Santa Cruz Biotechnology, Inc. offers a broad range of DRP1 antibodies. Select DRP1 antibodies from monoclonal antibodies listed below. View detailed DRP1 antibody specifications by linking to the specific product blocks. Select appropriate DRP1 antibodies for your research by isotype, epitope, applications and … nrcs homologation

ROS-mediated activation and mitochondrial translocation of …

WebFeb 2, 2024 · Similarly, NRF3 knockdown did not change the protein levels of Mitochondrial Fission Process 1 (MTFP1), which is increased by mTORC1 activation. 43 Meanwhile, we observed that NRF3 knockdown and rapamycin treatment increased the phosphorylation levels of DRP1 at S637 (p-DRP1 (S637)) (Figure S6E), attenuating the DRP1-mediated … WebRabbit polyclonal to DRP1 (phospho S637) Application: WB. Reactivity: Human (predicted: Mouse, Rat) Conjugate: Unconjugated. Recombinant. Anti-DRP1 antibody [EPR24461-48] - BSA and Azide free (Capture) (ab288722) Description: Rabbit monoclonal [EPR24461-48] to DRP1 - BSA and Azide free (Capture) Application: sELISA. nrcs homologation certificateWebMay 1, 2024 · U0126 reduces DRP1-S616, not -S637, phosphorylation level. SP600125 does not influence DRP1-S616 and -S637 phosphorylations. Okadaic acid and CsA increase DRP1-S616 and -S637 phosphorylation, respectively. (A) Representative images for western blot of DRP1, phospho (p)-DRP1-S616, pDRP1-S637, ERK1/2, pERK1/2, JNK, … nightjar barb feathers

"WebPhospho-DRP1-S637 Polyclonal Antibody. Unconjugated. Raised in: Rabbit. Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity Human, Mouse, … " - Drp1 phospho s637

Drp1 phospho s637

DRP1 (phospho Ser637) Polyclonal Antibody

WebBoster Bio Anti-Phospho-DRP1 (S637) DNM1L Antibody catalog # A00556S637-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied … WebFeb 10, 2024 · a Representative immunoblotting of phospho-Drp1 on serine 616 (p-Drp1-S616) and serine 637 (p-Drp1-S637) and total Drp1 in Tibialis Anterior (TA) lysates from …

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WebAnti-DRP1 (phospho S637) antibody (ab193216) Datasheet. SDS. Reviews ( 4) Submit a question References (21) $585 Product size. 100 µl. Add to basket. Order now and get it … WebA synthetic phosphorylated peptide around S637 of human DRP1 (NP_036192.2). Sequence: KLSAR: Gene ID: 10059: Swiss prot: O00429: Synonyms: DNM1L; DLP1; …

WebJan 8, 2024 · On the other hand, phospho-S637 Drp1 was not detectable after 10 Gy irradiation. Furthermore, while Drp1 phosphorylation at S616 increased in a dose-dependent manner, phospho-S637 Drp1 level was unaffected by X-irradiation at any dose (Fig. 1 B). These results demonstrate that IR stimulates Drp1 phosphorylation at S616, but not at … WebOct 14, 2008 · Immunoblotting of total lysates with an anti phospho-Serine 637 antibody indicated that after ArA treatment this residue becomes ... S616 and S637. While Drp1 S616-YFP mutants behaved in an almost superimposable manner to that of wt Drp1-YFP, mutagenesis of S637 had a major impact on subcellular localization and mitochondrial …

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WebAug 16, 2024 · As this was unexpected, trends were confirmed with a second phospho-Drp1-S637 antibody. QLR-dependent re-activation of MTORC1 was confirmed in these samples. Since QLR-dependent …

Web②细胞质基质中drp1的s616位点磷酸化，可以使drp1定位于线粒体外膜上，促进线粒体 _____ （填“分裂”或“融合”）。 ③线粒体外膜上的蛋白 _________ 、内膜融合蛋白QPA1共同作用实现了线粒体膜的融合，使线粒体的长度明显变长。 nrcs holiday payWebMay 18, 2016 · Therefore, DRP1 S616/S637 phosphorylation ratio is one of the indicatives for the capacity of DRP1-mediated mitochondrial dynamics (Kim et al., 2014a). To elucidate the relationship between mitochondrial … nrcs honey beeWebFeb 19, 2024 · Exposure of cells to arnidiol resulted in decreases in the levels of phospho-Drp1 (Ser637) and phospho-cofilin (Ser3) in a dose- and time-dependent manner. In contrast, ... Taken together, these findings indicate that the dephosphorylation of both Drp1 (S637) and cofilin (Ser3) is required for the mitochondrial translocation of Drp1 and cofilin ... nightjar bird mouthWebPolyclonal Antibody for studying DRP1 (Ser637) phosphate. Cited in 138 publications. Validated for Western Blotting, Immunoprecipitation. Highly … nrcs honey bee initiativeWebMay 28, 2024 · c Whole cellular lysates (WCL) and cytosolic (Cyto)/mitochondrial (Mito) fractions were prepared and subjected to Western blot using antibodies against phospho-Drp1 (p-Drp1) (S616), p-Drp1 (S637), and Drp1. d The colocalization of Drp1 (green) and MitoTracker (red) was examined using confocal microscopy. Scale bars: 10 μm. nrcs honoluluWebWestern blot analysis of JK cells using Phospho-DRP1 (S637) Polyclonal Antibody Anti-Phospho-DNM1L-Ser637 antibody (580-660) (STJ91001) SKU: STJ91001. £42.00 - £189.00 ) Current Stock: ... Synthesized phospho-peptide around the phosphorylation site of human DRP1 (phospho Ser637) nightjar close farnborough nightjar soundcloud